a final risk characterization.

a final risk characterization.

You may NOT use any of these case studies for your research project.

Staged Project (Case Study 1), Stage 1: Define the purpose of the Risk Assessment. Apply the steps of hazard identification to identify the hazard in each case study. Be sure to discuss the evidence that led you to your decision about the identification of the hazard. If the case study doesn’t provide the evidence then discuss how you would go about getting the evidence you need and what source would you use. Discuss how the evidence supports your conclusion about the identification of the hazard. Keep in mind the information you need for toxickinetics and toxicodynamics.

Staged Project (Case Study 2), Stage 2: Exposure assessment, dose-response assessment and risk characterization. Based on the case studies above and the hazard identified, discuss how you would approach an exposure assessment, a dose-response assessment and a final risk characterization.

NOTE: not all of these case studies are real incidences. You have been given choices so that you may explore areas within your interests.

Choose ONE study from EACH AREA below (this means you will comment on THREE case studies – one from community-based, one from work-based and one from medically based.

Community-Based Hazard Exposure:

Choose one (1) of these –

A. http://www.ops.fhwa.dot.gov/publications/fhwahop08014/case4_0.htm

Graniteville, S. Carolina Case study, Chlorine

Note that this case study either tells you, or strongly hints at what the hazard is. Ignore this, and tell me what logic you used to determine what the hazard actually was.

B. http://www.mhhe.com/Enviro-Sci/CaseStudyLibrary/Topic-Based/CaseStudy_LoveCanal.pdf

New York Case Study, water and ground pollution

Workplace-Based Hazard Exposure:

Choose one (1) of these –

A: An employee developed occupational asthma after working for a large multi-national company in Gloucester. He was employed between 1995 and 2004 as a solderer and was exposed to rosin based (colophony) solder fume during his career. The company had no fume extraction equipment to remove rosin based fumes from the workroom air or from the breathing zones of its solderers.

His health was deteriorating from 1999 onwards and he was taking time off work due to breathing difficulties.

B: Jenkins Chemical

Background

Jenkins Chemicals is a small/medium size specialist chemical manufacturing

company based in Hartfordshire, England. The company supplies Hydrazine Hydrate (a known carcinogen) for use as an oxygen scavenger of boiler feed water, preventing corrosion damage in high pressure boilers used in the power generating industries and used as a chemical intermediate for a number of different applications. Under the Chemicals (Hazard Information and Packaging for Supply) Regulations, Hydrazine Hydrate is a Category 2 carcinogen – believed to cause cancer in humans. Whilst under the EU Classification Labeling and Packaging regulations it will carry a category 1B (H350) Carcinogen classification.

The Problem