potential from negative to positive

What causes the rapid change in the resting membrane potential to initiate an action potential?

Question 1 options:

Potassium gates open and potassium rushes into the cell, changing the membrane potential from negative to positive

Sodium gates open and sodium rushes into the cell, changing the membrane potential from negative to positive.

Sodium gates close, allowing potassium into the cell to change the membrane potential from positive to negative.

Potassium gates close, allowing sodium into the cell to change the membrane potential from positive to negative.

Question 2

What is a consequence of leakage of lysosomal enzymes during chemical injury?

Question 2 options:

Enzymatic digestion of the nucleus and nucleolus occurs, halting deoxyribonucleic acid (DNA) synthesis.

Influx of potassium ions into the mitochondria occurs, halting the adenosine triphosphate (ATP) production.

Edema of the Golgi body occurs, preventing the transport of proteins out of the cell.