Inflammation and Immune FunctionAukley

Inflammation and Immune FunctionAukley

Physiologic changes in Inflammation and Immune FunctionAukley (2018) discusses the relationship between sleep deprivation and immune function. In studies involving animal models there was shown to be a link between impaired immune function and a loss of sleep (Aukley, 2018). Asif, Iqbal, and Nazir (2017) inform us that wakefulness, rapid eye movement and non-rapid eye movement regulate the immune response. Inflammatory mediators increase in response to sleep loss (Asif, Iqbal, & Nazir, 2017).In addition to regulation of sleep, melatonin, a pineal hormone plays a role in immune system regulation (Jehan et al., 2017). Melatonin has been known to assist with sleep deprivation and related immune challenges (Jehan et al., 2017)

.References

Asif, N., Iqbal, R., & Nazir, C. F. (2017). Human immune system during sleep. American journal of clinical and experimental immunology, 6(6), 92–96.Aukley, D. (2018). Poor sleep in the hospital: Contributing factors and interventions. Retrieved from https://www.uptodate.com/contents/poor-sleep-in-the-hospital-contributing-factors-and-interventions?search=inadequate sleep&source=search_result&selectedTitle=2~150&usage_type=default&display_rank=2Baker,

F. C., de Zambotti, M., Colrain, I. M., & Bei, B. (2018). Sleep problems during the menopausal transition: prevalence, impact, and management challenges. Nature and science of sleep, 10, 73–95. doi:10.2147/NSS.S125807Javaheri, S., & Redline, S. (2017). Insomnia and Risk of Cardiovascular Disease. Chest, 152(2), 435–444. doi:10.1016/j.chest.2017.01.026Jehan,

S., Jean-Louis, G., Zizi, F., Auguste, E., Pandi-Perumal, S. R., Gupta, R., … Brzezinski, A. (2017). Sleep, Melatonin, and the Menopausal Transition: What Are the Links?. Sleep science (Sao Paulo, Brazil), 10(1), 11–18. doi:10.5935/1984-0063.20170003