examination, the endocrinologist

examination, the endocrinologist

Following the initial consultation and examination, the endocrinologist ordered tests to determine whether Michael has a hyperthyroid. The test results indicated an elevation in the concentration of thyroid hormones in the blood and the presence of thyroid-stimulating antibodies. These antibodies specifically stimulate the thyroid gland by binding with the thyroid stimulating hormone receptor located on the plasma membrane of the follicular cells of the thyroid gland. Based on these results, the endocrinologist concluded that Michael has Grave’s disease, a form of hyperthyroidism believed to be autoimmune in nature. Michael was presented with a number of possible treatment options. These included treatment with chemicals (propylthiouracil and methimazole) that decrease the production of thyroid hormones by the thyroid gland, radioisotopic destruction of the thyroid gland by the use of 131I, and surgical removal of the thyroid gland. After considering all the options, especially the possible effects of radiation on gamete development, Michael chose surgery. Following successful surgery, Michael was prescribed synthetic thyroid hormone to ensure that his body was receiving adequate thyroid hormone and was told to return within 2 months for a follow-up evaluation of circulating thyroid hormone concentrations. He was also cautioned to carefully monitor his calcium intake.

Using the the terms covered this week answer the following questions about this case:

Why would an imbalance in thyroid hormones have such a widespread effect on the body? Why was a goiter observed in Michael’s neck? Given that Michael and his wife may want to have more children, why was radioisotope, for the destruction of the thyroid gland, ruled out?

Here are the discussion board requirements.

The initial discussion post must be at least 250 words of content, referencing the reading of the week, and include a scholarly source.